Product Name: Cytidine
CAS: 65-46-3
MF: C9H13N3O5
MW: 243.22
EINECS: 200-610-9
Appearance: White to almost white powder
Cytidine, a pyrimidine nucleoside, primarily serves as a key starting material for producing intermediates of anti-tumor and anti-viral drugs. Manufacturers use it to synthesize important pharmaceutical compounds, such as cytarabine (Ara-CR), cyclocytidine (CycloC), cytidine triphosphate (CTP), and CDP-choline. These substances then form the core active ingredients of various medicines.
Application: Raw materials for drug synthesis and biochemical reagents
Upstream product: Cytosine
Downstream products: CTP, CDP-choline, 2′, 3′-dodeoxycytidine, cytarabine, etc.
It is a fundamental nucleoside, consisting of the nucleobase cytosine linked to a ribose sugar molecule. It serves as a vital building block in both biochemistry and the pharmaceutical industry.

Primarily, it is a direct precursor for the synthesis of cytidine triphosphate (CTP), a crucial molecule for RNA production. Cells require a constant supply of it for normal genetic processes and cellular function. Beyond its natural role, however, it holds immense value as a key pharmaceutical intermediate.
Specifically, the pharmaceutical industry utilizes cytidine as a core starting material for manufacturing several important antiviral and anticancer drugs. For instance, scientists chemically modify the cytidine structure to produce potent medications. A prominent example is the synthesis of cytarabine (Ara-C), a cornerstone chemotherapy agent used primarily to treat certain leukemias. The structural similarity between cytidine and cytarabine allows the drug to interfere with DNA replication in rapidly dividing cancer cells.
Furthermore, it derivatives play a critical role in antiviral therapy. Modifications to the cytidine molecule can yield compounds that effectively inhibit viral replication. Notable drugs developed from it include lamivudine (3TC) and emtricitabine, which are essential components in standard combination therapies for HIV and hepatitis B.
In summary, while it is a natural biochemical, its true industrial significance lies in its role as a versatile scaffold. This makes it an indispensable and high-value starting point for producing life-saving medicines that combat serious diseases like cancer and viral infections.
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