Product Name: 2,5-Dimethoxybenzaldehyde
CAS: 93-02-7
MF: C9H10O3
MW: 166.17
EINECS: 202-211-5
Appearance: Light yellow crystalline powder
2,5-Dimethoxybenzaldehyde is an organic compound and a benzaldehyde derivative. One of its uses is the production of 2,5-dimethoxyphenethylamine, also known as 2C-H.
2,5-Dimethoxybenzaldehyde is a versatile organic compound. Chemists classify it as a benzaldehyde derivative. Essentially, it features a central benzene ring with an aldehyde group and two methoxy units. Specifically, these methoxy groups attach to the second and fifth carbon positions.

This compound typically appears as a pale yellow or white crystalline solid. It often has a subtle, sweet, and aromatic odor. The molecular structure governs its key properties. For instance, the electron-donating methoxy groups significantly influence the benzene ring’s reactivity. Consequently, the aldehyde group becomes less electrophilic compared to plain benzaldehyde. This alteration makes the compound less reactive in certain addition reactions but more suitable for selective substitutions.
Regarding its synthesis, several methods exist. A common approach involves the formylation of 1,4-dimethoxybenzene. Alternatively, selective methylation of hydroxybenzaldehydes is another viable route. The compound shows moderate stability under standard conditions but requires protection from prolonged light exposure.
Primarily, 2,5-dimethoxybenzaldehyde serves as a crucial building block in organic synthesis. The pharmaceutical industry values it highly as a key intermediate. For example, it is fundamental in creating certain vasodilator medications. Additionally, agrochemical production utilizes this compound for developing specific herbicides and fungicides.
Furthermore, the fragrance and dye industries find applications for it. Its distinct aromatic structure contributes to complex scent profiles and specialized dyes. In research laboratories, scientists frequently use it to synthesize more complex molecules, particularly various heterocycles and fine chemicals.
In summary, 2,5-dimethoxybenzaldehyde is an important synthetic intermediate. Its unique electronic structure enables diverse applications across multiple industries, from medicine to manufacturing.
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